Wolfgang Zacharias Selected Research

Cystatin M

1/2006	Silencing of cystatin M in metastatic oral cancer cell line MDA-686Ln by siRNA increases cysteine proteinases and legumain activities, cell proliferation and in vitro invasion.
1/2005	Expression analysis of cystatin C and M in laser-capture microdissectioned human breast cancer cells--a preliminary study.
9/2003	Upregulation of cystatin M during the progression of oropharyngeal squamous cell carcinoma from primary tumor to metastasis.

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Wolfgang Zacharias Research Topics

Disease

17	Neoplasms (Cancer) 05/2018 - 04/2003
8	Squamous Cell Carcinoma of Head and Neck 02/2013 - 09/2003
8	Neoplasm Metastasis (Metastasis) 01/2012 - 09/2003
8	Mouth Neoplasms (Oral Cancer) 06/2007 - 12/2004
5	Melanoma (Melanoma, Malignant) 12/2020 - 01/2012
5	Carcinoma (Carcinomatosis) 05/2014 - 04/2005
4	Hypoxia (Hypoxemia) 04/2011 - 12/2004
4	Carcinogenesis 04/2007 - 04/2006
3	Lymphatic Metastasis 05/2018 - 07/2005
2	Infections 01/2021 - 01/2005
1	COVID-19 01/2021
1	Lung Neoplasms (Lung Cancer) 01/2020
1	Albuminuria 01/2011
1	Inflammation (Inflammations) 01/2011
1	Diabetic Nephropathies (Diabetic Nephropathy) 01/2011
1	Leukoplakia 04/2006
1	Oral Lichen Planus 04/2006
1	Colonic Neoplasms (Colon Cancer) 12/2005
1	Breast Neoplasms (Breast Cancer) 01/2005
1	Rheumatoid Arthritis 05/2004
1	Atherosclerosis 02/2004
1	Leukemia 02/2004
1	Acquired Immunodeficiency Syndrome (AIDS) 09/2003
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 09/2003
1	Prostatic Neoplasms (Prostate Cancer) 04/2003
1	Endometriosis 04/2003
1	Precocious Puberty 04/2003

Drug/Important Bio-Agent (IBA)

8	Cathepsin BIBA 04/2007 - 09/2003
6	Proteins (Proteins, Gene)FDA Link 01/2012 - 01/2005
5	RNA (Ribonucleic Acid)IBA 12/2020 - 04/2005
4	Messenger RNA (mRNA)IBA 01/2012 - 09/2003
4	LigandsIBA 06/2007 - 01/2005
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 06/2007 - 01/2005
4	CathepsinsIBA 04/2007 - 01/2005
3	SmokeIBA 02/2013 - 08/2006
3	CarcinogensIBA 04/2007 - 08/2006
3	Peptide Hydrolases (Proteases)FDA Link 04/2007 - 04/2005
3	Cystatin MIBA 01/2006 - 09/2003
3	CystatinsIBA 07/2005 - 01/2005
2	Artificial SalivaIBA 05/2014 - 02/2013
2	Particulate MatterIBA 05/2014 - 02/2013
2	MicroRNAs (MicroRNA)IBA 01/2012 - 01/2011
2	Biological ProductsIBA 01/2011 - 01/2005
2	Cystatin CIBA 07/2005 - 01/2005
2	Catalytic RNA (Ribozymes)IBA 04/2005 - 05/2004
1	InterferonsIBA 01/2021
1	Antiviral Agents (Antivirals)IBA 01/2021
1	LipopolysaccharidesIBA 01/2020
1	Nicotine FDA Link 05/2014
1	Conditioned Culture MediaIBA 02/2013
1	Endoplasmic Reticulum Chaperone BiPIBA 01/2012
1	Pharmaceutical PreparationsIBA 01/2012
1	Biomarkers (Surrogate Marker)IBA 01/2012
1	Annexin A1IBA 01/2012
1	Annexin A2 (Annexin II)IBA 01/2012
1	ProteomeIBA 01/2012
1	SynteninsIBA 01/2012
1	Carbonic Anhydrase IXIBA 04/2011
1	pimonidazoleIBA 04/2011
1	cobaltous chloride (cobalt(II)chloride)IBA 04/2011
1	Vitamin D FDA LinkGeneric 01/2011
1	AlbuminsIBA 01/2011
1	Caspase 3 (Caspase-3)IBA 06/2007
1	CaspasesIBA 01/2007
1	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketoneIBA 01/2007
1	CA 074 methyl esterIBA 01/2007
1	pepstatin (pepstatin A)IBA 01/2007
1	Cytochromes c (Cytochrome c)IBA 01/2007
1	ArsenicIBA 09/2006
1	Aldo-Keto ReductasesIBA 08/2006
1	CytochromesIBA 08/2006
1	Basigin (Extracellular Matrix Metalloproteinase Inducer (EMMPRIN))IBA 04/2006
1	EnzymesIBA 03/2006
1	Cysteine Proteases (Cysteine Protease)IBA 01/2006
1	asparaginylendopeptidase (legumain)IBA 01/2006
1	Small Interfering RNA (siRNA)IBA 01/2006
1	Irinotecan (Camptosar)FDA LinkGeneric 12/2005
1	Cystatin BIBA 07/2005
1	Oxygen (Dioxygen)IBA 07/2005
1	thymosin beta(4)IBA 02/2005
1	Laminin ReceptorsIBA 02/2005
1	Transcription Factors (Transcription Factor)IBA 01/2005
1	TNF-Related Apoptosis-Inducing Ligand ReceptorsIBA 01/2005
1	Matrix Metalloproteinase 1 (Interstitial Collagenase)IBA 05/2004
1	Apolipoproteins E (ApoE)IBA 02/2004
1	Chemotactic FactorsIBA 02/2004
1	Leukotriene B4 Receptors (Leukotriene B4 Receptor)IBA 02/2004
1	ChemokinesIBA 02/2004
1	ApolipoproteinsIBA 02/2004
1	Leukotriene B4IBA 02/2004
1	Fatty Acids (Saturated Fatty Acids)IBA 02/2004
1	GonadotropinsIBA 04/2003
1	Gonadotropin-Releasing Hormone (GnRH)FDA Link 04/2003
1	Hormones (Hormone)IBA 04/2003

Therapy/Procedure

3	Therapeutics 01/2017 - 01/2007
1	Lymph Node Excision (Lymph Node Dissection) 05/2018
1	Lasers (Laser) 01/2005
1	Combination Drug Therapy (Combination Chemotherapy) 12/2004
1	Drug Therapy (Chemotherapy) 12/2004